TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION

Eric J. Weinlander; Angeline L. Wang; Pimkwan Jaru-Ampornpan; Michael M. Altaweel; T. Michael Nork

doi:10.1097/ICB.0000000000000567

TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION

Eric J. Weinlander
, Angeline L. Wang
, Pimkwan Jaru-Ampornpan
, Michael M. Altaweel
, T. Michael Nork

University of Wisconsin-Madison

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.

Original language	English
Pages (from-to)	241-243
Number of pages	3
Journal	Retinal Cases and Brief Reports
Volume	13
Issue number	3
DOIs	https://doi.org/10.1097/ICB.0000000000000567
Publication status	Published - 1 Jun 2019
Externally published	Yes

Keywords

acute retinal necrosis
prior shingles vaccination
varicella zoster virus

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10.1097/ICB.0000000000000567

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title = "TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION",

abstract = "Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.",

keywords = "acute retinal necrosis, prior shingles vaccination, varicella zoster virus",

author = "Weinlander, \{Eric J.\} and Wang, \{Angeline L.\} and Pimkwan Jaru-Ampornpan and Altaweel, \{Michael M.\} and Nork, \{T. Michael\}",

note = "Publisher Copyright: Copyright {\textcopyright} by Ophthalmic Communications Society, Inc. Unauthorized reproduction of this article is prohibited.",

year = "2019",

month = jun,

day = "1",

doi = "10.1097/ICB.0000000000000567",

language = "English",

volume = "13",

pages = "241--243",

journal = "Retinal Cases and Brief Reports",

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T1 - TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION

AU - Weinlander, Eric J.

AU - Wang, Angeline L.

AU - Jaru-Ampornpan, Pimkwan

AU - Altaweel, Michael M.

AU - Nork, T. Michael

PY - 2019/6/1

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N2 - Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.

AB - Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.

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KW - prior shingles vaccination

KW - varicella zoster virus

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DO - 10.1097/ICB.0000000000000567

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VL - 13

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TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION

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Keywords

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