The incidence of trophoblastic disease in Siriraj hospital

An analysis of 447 cases of trophoblastic disease observed in Bangkok, between January 1966 to December 1972 is presented. Of these 447 cases there were hydatiform mole 75.84%, chorioadenoma destruens 6.93% and 17.23% of choriocarcinoma. In the same period 122,093 hospital pregnancies, 118,505 hospital deliveries and 4,488 hospital abortions were managed. The incidence is 1:363 hospital pregnancies for hydatidiform mole, 1:3,938 hospital pregnancies for chorioadenoma destruens and 1:1,589 hospital pregnancies for choriocarcinoma. Geographic incidence of trophoblastic disease is discussed. The reasons for a wide geographic variation in incidence of trophoblastic disease are still unknown.