The floccular syndrome in herpes simplex type 1 encephalitis

Aasef G. Shaikh; Pichet Termsarasab; David E. Riley; Bashar Katirji

doi:10.1016/j.jns.2012.11.002

The floccular syndrome in herpes simplex type 1 encephalitis

Aasef G. Shaikh
, Pichet Termsarasab
, David E. Riley
, Bashar Katirji

Case Western Reserve University

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A woman with herpes simplex virus type 1 (HSV1) encephalitis had downbeat nystagmus. The nystagmus was robust in primary gaze but attenuated during upgaze, suggestive of the flocculus involvement. FLAIR and T2-sequences of the brain MRI revealed cerebral lesions typical of HSV1, but also patchy hyperintensities in bilateral flocculi. Cerebrospinal fluid polymerase chain reaction confirmed HSV1 infection. Encephalopathy and downbeat nystagmus gradually improved with acyclovir therapy.

Original language	English
Pages (from-to)	154-155
Number of pages	2
Journal	Journal of the Neurological Sciences
Volume	325
Issue number	1-2
DOIs	https://doi.org/10.1016/j.jns.2012.11.002
Publication status	Published - 15 Feb 2013
Externally published	Yes

Keywords

Cerebellum
Downbeat nystagmus
Oscillopsia
Vertigo

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10.1016/j.jns.2012.11.002

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title = "The floccular syndrome in herpes simplex type 1 encephalitis",

abstract = "A woman with herpes simplex virus type 1 (HSV1) encephalitis had downbeat nystagmus. The nystagmus was robust in primary gaze but attenuated during upgaze, suggestive of the flocculus involvement. FLAIR and T2-sequences of the brain MRI revealed cerebral lesions typical of HSV1, but also patchy hyperintensities in bilateral flocculi. Cerebrospinal fluid polymerase chain reaction confirmed HSV1 infection. Encephalopathy and downbeat nystagmus gradually improved with acyclovir therapy.",

keywords = "Cerebellum, Downbeat nystagmus, Oscillopsia, Vertigo",

author = "Shaikh, \{Aasef G.\} and Pichet Termsarasab and Riley, \{David E.\} and Bashar Katirji",

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doi = "10.1016/j.jns.2012.11.002",

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T1 - The floccular syndrome in herpes simplex type 1 encephalitis

AU - Shaikh, Aasef G.

AU - Termsarasab, Pichet

AU - Riley, David E.

AU - Katirji, Bashar

PY - 2013/2/15

Y1 - 2013/2/15

N2 - A woman with herpes simplex virus type 1 (HSV1) encephalitis had downbeat nystagmus. The nystagmus was robust in primary gaze but attenuated during upgaze, suggestive of the flocculus involvement. FLAIR and T2-sequences of the brain MRI revealed cerebral lesions typical of HSV1, but also patchy hyperintensities in bilateral flocculi. Cerebrospinal fluid polymerase chain reaction confirmed HSV1 infection. Encephalopathy and downbeat nystagmus gradually improved with acyclovir therapy.

AB - A woman with herpes simplex virus type 1 (HSV1) encephalitis had downbeat nystagmus. The nystagmus was robust in primary gaze but attenuated during upgaze, suggestive of the flocculus involvement. FLAIR and T2-sequences of the brain MRI revealed cerebral lesions typical of HSV1, but also patchy hyperintensities in bilateral flocculi. Cerebrospinal fluid polymerase chain reaction confirmed HSV1 infection. Encephalopathy and downbeat nystagmus gradually improved with acyclovir therapy.

KW - Cerebellum

KW - Downbeat nystagmus

KW - Oscillopsia

KW - Vertigo

UR - https://www.scopus.com/pages/publications/84872929779

U2 - 10.1016/j.jns.2012.11.002

DO - 10.1016/j.jns.2012.11.002

M3 - Article

C2 - 23218757

AN - SCOPUS:84872929779

SN - 0022-510X

VL - 325

SP - 154

EP - 155

JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

IS - 1-2

ER -

The floccular syndrome in herpes simplex type 1 encephalitis

Abstract

Keywords

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