Rhodol-based fluorescent probe for Au3+ detection and its application in bioimaging

Kanokorn Wechakorn; Samran Prabpai; Kanoknetr Suksen; Pawinee Piyachaturawat; Palangpon Kongsaeree

doi:10.1039/c6ra02342h

Rhodol-based fluorescent probe for Au³⁺ detection and its application in bioimaging

Kanokorn Wechakorn
, Samran Prabpai
, Kanoknetr Suksen
, Pawinee Piyachaturawat
, Palangpon Kongsaeree

Mahidol University

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

A turn-on fluorescent probe of propargyl-rhodol conjugate responds selectively to Au³⁺. In the presence of Au³⁺, the chemodosimeter undergoes a remarkable change in its absorption spectrum with a 370-fold fluorescence enhancement. This reaction-based Au³⁺ chemodosimeter is highly sensitive with a detection limit of 7 ppb through an irreversible mechanism. Bioimaging of HeLa cells with this chemical probe has been successfully demonstrated.

Original language	English
Pages (from-to)	24752-24755
Number of pages	4
Journal	RSC Advances
Volume	6
Issue number	29
DOIs	https://doi.org/10.1039/c6ra02342h
Publication status	Published - 2016
Externally published	Yes

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10.1039/c6ra02342h

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abstract = "A turn-on fluorescent probe of propargyl-rhodol conjugate responds selectively to Au3+. In the presence of Au3+, the chemodosimeter undergoes a remarkable change in its absorption spectrum with a 370-fold fluorescence enhancement. This reaction-based Au3+ chemodosimeter is highly sensitive with a detection limit of 7 ppb through an irreversible mechanism. Bioimaging of HeLa cells with this chemical probe has been successfully demonstrated.",

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AU - Prabpai, Samran

AU - Suksen, Kanoknetr

AU - Piyachaturawat, Pawinee

AU - Kongsaeree, Palangpon

PY - 2016

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AB - A turn-on fluorescent probe of propargyl-rhodol conjugate responds selectively to Au3+. In the presence of Au3+, the chemodosimeter undergoes a remarkable change in its absorption spectrum with a 370-fold fluorescence enhancement. This reaction-based Au3+ chemodosimeter is highly sensitive with a detection limit of 7 ppb through an irreversible mechanism. Bioimaging of HeLa cells with this chemical probe has been successfully demonstrated.

UR - https://www.scopus.com/pages/publications/84960129487

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DO - 10.1039/c6ra02342h

M3 - Article

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ER -

Rhodol-based fluorescent probe for Au³⁺ detection and its application in bioimaging

Abstract

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