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Regioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid

  • Pakorn Bovonsombat
  • , Juthamard Leykajarakul
  • , Chiraphorn Khan
  • , Kawin Pla-on
  • , Michael M. Krause
  • , Pratheep Khanthapura
  • , Rameez Ali
  • , Niran Doowa
  • Mahidol University

Research output: Contribution to journalArticlepeer-review

50 Citations (Scopus)

Abstract

Mild and highly regioselective monoiodination of phenol and analogues is achieved in high to excellent yields at room temperature with a combination of stoichiometric p-toluenesulfonic acid and N-iodosuccinimide.

Original languageEnglish
Pages (from-to)2664-2667
Number of pages4
JournalTetrahedron Letters
Volume50
Issue number22
DOIs
Publication statusPublished - 3 Jun 2009

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