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Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2012-2014)

  • Michael C. Breadmore
  • , Ria Marni Tubaon
  • , Aliaa I. Shallan
  • , Sui Ching Phung
  • , Aemi S. Abdul Keyon
  • , Daniel Gstoettenmayr
  • , Pornpan Prapatpong
  • , Ala A. Alhusban
  • , Leila Ranjbar
  • , Hong Heng See
  • , Mohamed Dawod
  • , Joselito P. Quirino
  • School of Physical Science
  • University of Tasmania, Faculty of Science, Engineering & Technology
  • Faculty of Science
  • UTM Johor Bahru
  • Faculty of Health Sciences
  • University of Michigan, Ann Arbor
  • Department of Analytical Chemistry
  • Faculty of Pharmacy

Research output: Contribution to journal › Review article › peer-review

144 Citations (Scopus)

Abstract

One of the most cited limitations of capillary (and microchip) electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments in the field of on-line/in-line concentration methods, covering the period July 2012-July 2014. It includes developments in the field of stacking, covering all methods from field-amplified sample stacking and large-volume sample stacking, through to ITP, dynamic pH junction, and sweeping. Attention is also given to on-line or in-line extraction methods that have been used for electrophoresis.

Original languageEnglish
Pages (from-to)36-61
Number of pages26
JournalElectrophoresis
Volume36
Issue number1
DOIs
Publication statusPublished - 1 Jan 2015

Keywords

  • Extraction
  • Focusing
  • Preconcentration
  • Stacking
  • Sweeping

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