TY - GEN
T1 - Pro-oxidative activity in some Thai spices
AU - Dumri, Kanchana
AU - Lertsiri, Sittiwat
PY - 2005
Y1 - 2005
N2 - Twenty methanolic extracts from Thai spice powder (anise, cardamom, chilli, Chinese key, cinnamon, clove, coriander, cumin, deeplee, dill, fennel, galangal, kencur, lemongrass, ginger, nutmeg, oregano, pepper, safflower, and turmeric) were screened for pro-oxidative activity using a lecithin-liposome model system. The oxidative stress was induced by four systems: (I) non-metal induction; (II) FeCl3/H2O2/EDTA; (III) FeSO4/ascorbate; and (IV) CuSO4/H2O 2. Of these spices, safflower, lemongrass, and nutmeg extracts showed the pro-oxidative activity observed by thiobarbituric acid reactive substance elevation. Since pro-oxidation were metal dependent, hydroxyl radical formation was investigated by monitoring fluorescence products from benzoate hydroxylation. The formation of hydroxyl radical was confirmed with the fluorescence detected and the suppression due to addition of mannitol, a hydroxyl radical scavenger.
AB - Twenty methanolic extracts from Thai spice powder (anise, cardamom, chilli, Chinese key, cinnamon, clove, coriander, cumin, deeplee, dill, fennel, galangal, kencur, lemongrass, ginger, nutmeg, oregano, pepper, safflower, and turmeric) were screened for pro-oxidative activity using a lecithin-liposome model system. The oxidative stress was induced by four systems: (I) non-metal induction; (II) FeCl3/H2O2/EDTA; (III) FeSO4/ascorbate; and (IV) CuSO4/H2O 2. Of these spices, safflower, lemongrass, and nutmeg extracts showed the pro-oxidative activity observed by thiobarbituric acid reactive substance elevation. Since pro-oxidation were metal dependent, hydroxyl radical formation was investigated by monitoring fluorescence products from benzoate hydroxylation. The formation of hydroxyl radical was confirmed with the fluorescence detected and the suppression due to addition of mannitol, a hydroxyl radical scavenger.
KW - Hydroxyl radical
KW - Lemongrass
KW - Nutmeg
KW - Oxidative stress
KW - Safflower
UR - https://www.scopus.com/pages/publications/84879899851
U2 - 10.17660/ActaHortic.2005.680.2
DO - 10.17660/ActaHortic.2005.680.2
M3 - Conference contribution
AN - SCOPUS:84879899851
SN - 9789066055780
T3 - Acta Horticulturae
SP - 25
EP - 29
BT - III WOCMAP Congress on Medicinal and Aromatic Plants - Volume 6
PB - International Society for Horticultural Science
ER -