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Preparation and characterizations of electrospun lactide-based polymeric nanofibers

  • C. Thammawong
  • , A. Petchsuk
  • , M. Opaprakasit
  • , N. Chanunpanich
  • , P. Tangboriboonrat
  • , P. Opaprakasit
  • School of Biochemical Engineering and Technology
  • Sirindhorn International Institute of Technology, Thammasat University
  • Thailand Science Park
  • Laboratory of Advanced Chromic Materials
  • Chulalongkorn University
  • Industrial Chemistry Department
  • King Mongkut's University of Technology North Bangkok

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Poly(L)lactide (PLLA), aliphatic polyester, and poly(LLA-co-DLLA) copolymers consisting of 2.5, 7.5, 50% of DLLA content were also synthesized. PLLA was successfully electrospun by using 15wt% solution in (1DMF:3CHCl 3) mixed solvent. 2.5, 7.5, 50% P(LLA-co-DLLA) copolymers were then spun at 8, 10, and 15wt% concentration in a single chloroform solvent, respective. The lactide-based polymeric nanofibers were characterized by Scanning Electron Microscope (SEM). Smooth surface morphology was observed in nanofibers produced from PLLA and 50% P(LLA-co-DLLA) copolymer. However, surface porosity was observed in the corresponding fibers from 2.5 and 7.5% P(LLA-co-DLLA) copolymers. These nanofibers have high potential for wide range of applications such as filter media, nano-sensor, drug delivery and tissue scaffold, especially, those derived from 2.5 and 7.5% P(LLA-co-DLLA) copolymers which contain high degree of porosity

Original languageEnglish
Title of host publicationFunctionalized and Sensing Materials
Pages377-380
Number of pages4
DOIs
Publication statusPublished - 2010
EventInternational Conference on Functionalized and Sensing Materials, FuSeM 2009 - Bangkok, Thailand
Duration: 7 Dec 2009 → 9 Dec 2009

Publication series

NameAdvanced Materials Research
Volume93-94
ISSN (Print)1022-6680

Conference

ConferenceInternational Conference on Functionalized and Sensing Materials, FuSeM 2009
Country/TerritoryThailand
CityBangkok
Period7/12/09 → 9/12/09

Keywords

  • Copolymer
  • Electrospinning
  • Nanofiber
  • Polylactic acid
  • Porosity

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