Performance of the cryptococcal antigen lateral flow assay in non-HIV-related cryptococcosis

Anupop Jitmuang; Anil A. Panackal; Peter R. Williamson; John E. Bennett; John P. Dekker; Adrian M. Zelazny

doi:10.1128/JCM.02223-15

Performance of the cryptococcal antigen lateral flow assay in non-HIV-related cryptococcosis

Anupop Jitmuang
, Anil A. Panackal
, Peter R. Williamson
, John E. Bennett
, John P. Dekker
, Adrian M. Zelazny

National Institute of Allergy and Infectious Diseases (NIAID)
Foundation for Advanced Education in the Sciences at the NIH
Siriraj Hospital
Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.

Original language	English
Pages (from-to)	460-463
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	54
Issue number	2
DOIs	https://doi.org/10.1128/JCM.02223-15
Publication status	Published - Feb 2016
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.1128/JCM.02223-15

Cite this

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abstract = "The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.",

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AU - Dekker, John P.

AU - Zelazny, Adrian M.

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AB - The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.

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Performance of the cryptococcal antigen lateral flow assay in non-HIV-related cryptococcosis

Abstract

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