Narrow-Band Ultraviolet B Phototherapy in Vitiligo

Narumol Silpa‐archa; Henry W. Lim

doi:10.1002/9781118937303.ch12

Narrow-Band Ultraviolet B Phototherapy in Vitiligo

Narumol Silpa‐archa
, Henry W. Lim

Department of Dermatology

Henry Ford Health System

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Citations (Scopus)

Abstract

Various home phototherapy models are available, ranging from full body units, small panel, to handheld units. The Narrow-Band Ultraviolet B Phototherapy (NB-UVB) hand and foot unit can be used to treat vitiligo that is limited to the hands and feet. Other types of UV-based treatment for vitiligo include targeted phototherapy using excimer laser or excimer lamp, and PUVA. NB-UVB has an excellent safety profile, and can be administered to children, pregnant and lactating women, and patients with hepatic and renal diseases. Repigmentation begins at the hair follicle, where NB-UVB stimulates the activation, proliferation and migration of melanocytes from the outer root sheath to the adjacent epidermis. This chapter summarises the efficacy of NB-UVB monotherapy in adult and childhood vitiligo. Rotational treatment using phototherapy and medical treatments should be carried out to maintain repigmentation. The tacrolimus-treated patients showed a statistically significantly better median repigmentation.

Original language	English
Title of host publication	Vitiligo
Subtitle of host publication	Medical and Surgical Management
Publisher	wiley
Pages	93-103
Number of pages	11
ISBN (Electronic)	9781118937303
ISBN (Print)	9781118937419
DOIs	https://doi.org/10.1002/9781118937303.ch12
Publication status	Published - 1 Jan 2018

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abstract = "Various home phototherapy models are available, ranging from full body units, small panel, to handheld units. The Narrow-Band Ultraviolet B Phototherapy (NB-UVB) hand and foot unit can be used to treat vitiligo that is limited to the hands and feet. Other types of UV-based treatment for vitiligo include targeted phototherapy using excimer laser or excimer lamp, and PUVA. NB-UVB has an excellent safety profile, and can be administered to children, pregnant and lactating women, and patients with hepatic and renal diseases. Repigmentation begins at the hair follicle, where NB-UVB stimulates the activation, proliferation and migration of melanocytes from the outer root sheath to the adjacent epidermis. This chapter summarises the efficacy of NB-UVB monotherapy in adult and childhood vitiligo. Rotational treatment using phototherapy and medical treatments should be carried out to maintain repigmentation. The tacrolimus-treated patients showed a statistically significantly better median repigmentation.",

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Narrow-Band Ultraviolet B Phototherapy in Vitiligo

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