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Modeling the effects of parathyroid hormone and vitamin D on calcium homeostasis

  • Inthira Chaiya
  • , Chontita Rattanakul
  • , Sahattaya Rattanamongkonkul
  • , Wannapa Panitsupakamon
  • , Sittipong Ruktamatakul
  • Mahidol University
  • Burapha University
  • Silpakorn University
  • Kasetsart University

Research output: Contribution to journalArticlepeer-review

Abstract

Calcium homeostasis is an important mechanism in human being. The disorder of such mechanism may leads to serious diseases. In this paper, we propose a mathematical model to describe calcium homeostasis based on the effects of two major factors, parathyroid hormone and vitamin D. The various kinds of dynamics behavior are investigated both theoretically and numerically.

Original languageEnglish
Pages (from-to)745-754
Number of pages10
JournalInternational Journal of Mathematical Models and Methods in Applied Sciences
Volume7
Issue number8
Publication statusPublished - 2013

Keywords

  • Calcium homeostasis
  • Geometric singular perturbation
  • Parathyroid hormone
  • Vitamin D

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