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Microcapsule agglutination test for the diagnosis of leptospirosis in Thailand

  • Y. Suputtamongkol
  • , S. Sarawish
  • , S. Silpasakorn
  • , U. Potha
  • , K. Silpapojakul
  • , P. Naigowit
  • Siriraj Hospital
  • Faculty of Tropical Medicine, Mahidol University
  • Faculty of Medicine, Prince of Songkla University
  • Foundation for Advanced Education in the Sciences at the NIH

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Sera from 82 cases of leptospirosis (confirmed by micro-agglutination tests or IFAT) and 108 patients with other diseases were investigated using the microcapsule agglutination test (MCAT) for leptospirosis. The overall sensitivity (90.2%), specificity (96.3%), positive predictive value (94.9%), negative predictive value (92.9%), and accuracy of the MCAT (93.7%) were encouraging. MCAT is simple, can be performed by unskilled personnel with minimum laboratory facilities, and produces results in 3 h. MCAT would be a reliable serodiagnostic test for rapidly screening individuals for leptospirosis, in various geographical areas of Thailand.

Original languageEnglish
Pages (from-to)797-801
Number of pages5
JournalAnnals of Tropical Medicine and Parasitology
Volume92
Issue number7
DOIs
Publication statusPublished - 1998

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