Lesson Learned from Antiseptic Mouthwash in COVID-19 Pandemic Then, Now and Future: A Systematic Review

A new virus has been discovered, SARS-CoV-2 (severe acute respiratory syndrome coronavirus). SARS-CoV-2 is transmitted through aerosols or salivary droplets. Therefore, this may be a potential high-risk for viral infection and transmission in a dental clinic. After the pandemic we know that an oral viral load reduction could reduce the risk of transmission via saliva. Oral antiseptics seem to be one of useful methods in preventing viral transmission. The aim of this review was to evaluate the available evidence on the effectiveness of mouthwashes in dental care facilities. Methods: An electronic search was conducted using MEDLINE, Pubmed and Scopus databases, using systematic review method and review final information. After those we summarized results, discussed, and recommended for using proper mouthwash in dental field. A total of 308 articles were found. Six in vitro and six in vivo articles were selected, assessing the effectiveness of oral antiseptic mouthwashes. Conclusion: All documents clear evidence to support the use of antiseptics to potentially reduce the viral load of SARS-CoV-2. It is highly recommended that dental practitioners use oral antiseptics before dental procedures to protect against the transmission of Coronavirus virus and routine using in the future.