Abstract
This paper demonstrates the use of Guided Mode Resonance (GMR) optical sensor platform for detection of Glycated Hemoglobin (HbA1c) in human blood. HbA1c is an importance biomarker for monitoring a long-Term glucose level in diabetes patients. Here, the sensing approach utilizes boronate affinity by modification of the GMR surface with 3- Aminophenylboronic acid (PBA). The sensing signal is then measured via a resonance shift in a reflection spectrum as the change of the refractive index on the sensor surface. In preliminary experiment, standard HbA1c samples with concentration covering the detection range (5% and 10 %) are used. The results show a good trend of resonance shift corresponding to amount of HbA1c.
| Original language | English |
|---|---|
| Title of host publication | 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 1-2 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781509062904 |
| DOIs | |
| Publication status | Published - 22 Nov 2017 |
| Event | 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017 - Singapore, Singapore Duration: 31 Jul 2017 → 4 Aug 2017 |
Publication series
| Name | 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017 |
|---|---|
| Volume | 2017-January |
Conference
| Conference | 2017 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2017 |
|---|---|
| Country/Territory | Singapore |
| City | Singapore |
| Period | 31/07/17 → 4/08/17 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Keywords
- Boronate affinity
- Glycated hemoglobin
- Guided mode resonance
- Optical sensor
- Photonic crystals slab
Fingerprint
Dive into the research topics of 'Label-free guided mode resonance sensor for detection of glycated hemoglobin'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver