Isothiocyanatoluminol as a chemiluminescence labeling reagent for amino acids and proteins

Srung Smanmoo; Weerachai Nasomphan; Pramuan Tangboriboonrat

doi:10.1246/cl.2011.188

Isothiocyanatoluminol as a chemiluminescence labeling reagent for amino acids and proteins

Srung Smanmoo
, Weerachai Nasomphan
, Pramuan Tangboriboonrat

National Science and Technology Development Agency (NSTDA)
Mahidol University

Research output: Contribution to journal › Article › peer-review

Abstract

Isothiocyanatoluminol (ITL) was successfully synthesized from the reaction between luminol and thiophosgene in the presence of triethylamine. The optimized conditions were extended for the preparation of isothiocyanatoisoluminol (ITIL) and phenyl isothiocyanate (PI). The chemiluminescence (CL) of ITL was comparable to luminol. ITL was used as a CL labeling reagent for amino acid and bovine serum albumin (BSA) in which the -NH₂ terminus of amino acid residue present in BSA acts as the labeling site.

Original language	English
Pages (from-to)	188-190
Number of pages	3
Journal	Chemistry Letters
Volume	40
Issue number	2
DOIs	https://doi.org/10.1246/cl.2011.188
Publication status	Published - 2011
Externally published	Yes

Access to Document

10.1246/cl.2011.188

Cite this

@article{465c63bd083a43f5992da59c8a3e5e85,

title = "Isothiocyanatoluminol as a chemiluminescence labeling reagent for amino acids and proteins",

abstract = "Isothiocyanatoluminol (ITL) was successfully synthesized from the reaction between luminol and thiophosgene in the presence of triethylamine. The optimized conditions were extended for the preparation of isothiocyanatoisoluminol (ITIL) and phenyl isothiocyanate (PI). The chemiluminescence (CL) of ITL was comparable to luminol. ITL was used as a CL labeling reagent for amino acid and bovine serum albumin (BSA) in which the -NH2 terminus of amino acid residue present in BSA acts as the labeling site.",

author = "Srung Smanmoo and Weerachai Nasomphan and Pramuan Tangboriboonrat",

year = "2011",

doi = "10.1246/cl.2011.188",

language = "English",

volume = "40",

pages = "188--190",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "Oxford University Press",

number = "2",

}

TY - JOUR

T1 - Isothiocyanatoluminol as a chemiluminescence labeling reagent for amino acids and proteins

AU - Smanmoo, Srung

AU - Nasomphan, Weerachai

AU - Tangboriboonrat, Pramuan

PY - 2011

Y1 - 2011

N2 - Isothiocyanatoluminol (ITL) was successfully synthesized from the reaction between luminol and thiophosgene in the presence of triethylamine. The optimized conditions were extended for the preparation of isothiocyanatoisoluminol (ITIL) and phenyl isothiocyanate (PI). The chemiluminescence (CL) of ITL was comparable to luminol. ITL was used as a CL labeling reagent for amino acid and bovine serum albumin (BSA) in which the -NH2 terminus of amino acid residue present in BSA acts as the labeling site.

AB - Isothiocyanatoluminol (ITL) was successfully synthesized from the reaction between luminol and thiophosgene in the presence of triethylamine. The optimized conditions were extended for the preparation of isothiocyanatoisoluminol (ITIL) and phenyl isothiocyanate (PI). The chemiluminescence (CL) of ITL was comparable to luminol. ITL was used as a CL labeling reagent for amino acid and bovine serum albumin (BSA) in which the -NH2 terminus of amino acid residue present in BSA acts as the labeling site.

UR - https://www.scopus.com/pages/publications/79551471336

U2 - 10.1246/cl.2011.188

DO - 10.1246/cl.2011.188

M3 - Article

AN - SCOPUS:79551471336

SN - 0366-7022

VL - 40

SP - 188

EP - 190

JO - Chemistry Letters

JF - Chemistry Letters

IS - 2

ER -

Isothiocyanatoluminol as a chemiluminescence labeling reagent for amino acids and proteins

Abstract

Access to Document

Other files and links

Fingerprint

Cite this