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Iodine-catalyzed expeditious synthesis of sulfonamides from sulfonyl hydrazides and amines

  • Sirilata Yotphan
  • , Ladawan Sumunnee
  • , Danupat Beukeaw
  • , Chonchanok Buathongjan
  • , Vichai Reutrakul
  • Mahidol University

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)

Abstract

A new synthesis of sulfonamides has been developed via an iodine-catalyzed sulfonylation of amines with arylsulfonyl hydrazides. This metal-free strategy employs readily accessible and easy to handle starting materials, catalysts and oxidants, and can be easily conducted under mild conditions, providing a convenient access to a wide range of sulfonamides in moderate to excellent yields within a short reaction time.

Original languageEnglish
Pages (from-to)590-597
Number of pages8
JournalOrganic and Biomolecular Chemistry
Volume14
Issue number2
DOIs
Publication statusPublished - 2016
Externally publishedYes

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