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Imaging cell biology in live animals: Ready for prime time

  • National Institute of Dental and Craniofacial Research (NIDCR)

Research output: Contribution to journalReview articlepeer-review

104 Citations (Scopus)

Abstract

Time-lapse fluorescence microscopy is one of the main tools used to image subcellular structures in living cells. Yet for decades it has been applied primarily to in vitro model systems. Thanks to the most recent advancements in intravital microscopy, this approach has finally been extended to live rodents. This represents a major breakthrough that will provide unprecedented new opportunities to study mammalian cell biology in vivo and has already provided new insight in the fields of neurobiology, immunology, and cancer biology.

Original languageEnglish
Pages (from-to)969-979
Number of pages11
JournalJournal of Cell Biology
Volume201
Issue number7
DOIs
Publication statusPublished - Jun 2013
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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