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Hirsutellones A-E, antimycobacterial alkaloids from the insect pathogenic fungus Hirsutella nivea BCC 2594

  • Masahiko Isaka
  • , Nuntawan Rugseree
  • , Pacharee Maithip
  • , Palangpon Kongsaeree
  • , Samran Prabpai
  • , Yodhathai Thebtaranonth
  • National Science and Technology Development Agency (NSTDA)
  • Mahidol University

Research output: Contribution to journalArticlepeer-review

184 Citations (Scopus)

Abstract

Five new alkaloids, hirsutellones A-E, were isolated from the insect pathogenic fungus Hirsutella nivea BCC 2594. Their structures were elucidated by spectroscopic analysis and X-ray crystallography. Hirsutellones displayed significant growth inhibitory activity against Mycobacterium tuberculosis H 37Ra.

Original languageEnglish
Pages (from-to)5577-5583
Number of pages7
JournalTetrahedron
Volume61
Issue number23
DOIs
Publication statusPublished - 6 Jun 2005
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Antimycobacterial activity
  • Hirsutella nivea
  • Insect pathogenic fungi

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