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Exploring the Immune-Boosting Functions of Vitamins and Minerals as Nutritional Food Bioactive Compounds: A Comprehensive Review

  • Saikat Mitra
  • , Shyamjit Paul
  • , Sumon Roy
  • , Hriday Sutradhar
  • , Talha Bin Emran
  • , Firzan Nainu
  • , Mayeen Uddin Khandaker
  • , Mohammed Almalki
  • , Polrat Wilairatana
  • , Mohammad S. Mubarak
  • University of Dhaka
  • BGC Trust University Bangladesh
  • Hasanuddin University
  • Sunway University
  • Taif University
  • The University of Jordan

Research output: Contribution to journalReview articlepeer-review

132 Citations (Scopus)

Abstract

Food components have long been recognized to play a fundamental role in the growth and development of the human body, conferring protective functionalities against foreign matter that can be severe public health problems. Micronutrients such as vitamins and minerals are essential to the human body, and individuals must meet their daily requirements through dietary sources. Micronutrients act as immunomodulators and protect the host immune response, thus preventing immune evasion by pathogenic organisms. Several experimental investigations have been undertaken to appraise the immunomodulatory functions of vitamins and minerals. Based on these experimental findings, this review describes the immune-boosting functionalities of micronutrients and the mechanisms of action through which these functions are mediated. Deficiencies of vitamins and minerals in plasma concentrations can lead to a reduction in the performance of the immune system functioning, representing a key contributor to unfavorable immunological states. This review provides a descriptive overview of the characteristics of the immune system and the utilization of micronutrients (vitamins and minerals) in preventative strategies designed to reduce morbidity and mortality among patients suffering from immune invasions or autoimmune disorders.

Original languageEnglish
Article number555
JournalMolecules
Volume27
Issue number2
DOIs
Publication statusPublished - 1 Jan 2022

Keywords

  • Food bioactive compounds
  • Immune system
  • Minerals
  • Nutrition
  • Vitamins

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