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Epidemiology of adult patients with atopic dermatitis in AWARE 1: A second international survey

  • Jorge Maspero
  • , Norma De Paula Motta Rubini
  • , Jianzhong Zhang
  • , Gloria Sanclemente
  • , Julio Roberto Amador
  • , Mahira Hamdy El Sayed
  • , Alson Chan Wai Ming
  • , Roni P. Dodiuk-Gad
  • , Issam Hamadah
  • , Suganthi Thevarajah
  • , Catalina Rincón-Perez
  • , Elena Fedenko
  • , Yik Weng Yew
  • , Mark B.Y. Tang
  • , Chia Yu Chu
  • , Kanokvalai Kulthanan
  • , Ozlem Su Kucuk
  • , Anwar Al-Hammadi
  • , Lysel Brignoli
  • , Angelina Tsankova
  • Sarah El-Samad, Jose Eduardo Neves, Laurent Eckert
  • University of Buenos Aires
  • Federal University of Rio de Janeiro
  • Peking University Peopleʼs Hospital
  • Universidad de Antioquia
  • Universidad Militar Nueva Granada
  • Ain Shams University
  • Hong Kong Sanatorium and Hospital
  • HaEmek Medical Center
  • King Faisal Specialist Hospital and Research Center
  • Kuala Lumpur Hospital
  • Ministry of National Defense
  • National Research Center-Institute of Immunology Federal Medical-Biological Agency of Russia
  • National Skin Centre, Singapore
  • Mount Alvernia Hospital
  • National Taiwan University College of Medicine
  • Bezmialem Vakif University
  • Dubai Medical Center
  • Kantar Health
  • Sanofi S.A.
  • Sanofi

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Background: There are gaps in our understanding of the epidemiology of atopic dermatitis (AD) in adults. Objective: To evaluate the prevalence and severity of AD in adults from countries/regions within Asia, Eurasia, Latin America, Middle East, and Russia. Methods: This international, web-based survey was performed in Argentina, Brazil, China, Colombia, Egypt, Hong Kong, Israel, Malaysia, Mexico, Russia, Kingdom of Saudi Arabia (KSA), Singapore, Taiwan, Thailand, Turkey, and United Arab Emirates. Questionnaires were sent to adult members of online respondent panels for determination of AD and assessment of severity. A diagnosis of AD required respondents to meet the modified United Kingdom (UK) Working Party criteria and to self-report they had a physician diagnosis of AD. Severity of AD was determined using Patient-Oriented Scoring of Atopic Dermatitis (PO-SCORAD), Patient-Oriented Eczema Measure (POEM), and Patient Global Assessment (PGA). Results: Among respondents by country/region the prevalence of AD ranged from 3.4% in Israel to 33.7% in Thailand. The prevalence was generally higher in females versus males. Severity varied by scale, although regardless of scale the proportion of respondents with mild and moderate disease was higher than severe disease. PGA consistently resulted in the lowest proportion of severe AD (range 2.4% China – 10.8% Turkey) relative to PO-SCORAD (range 13.4% China – 41.6% KSA) and POEM (range 5.1% China – 16.6% Israel). Conclusions: This survey highlights the importance of AD in adults, with high prevalence and high morbidity among respondents and emphasizes that AD is not just a disease of childhood—there is disease persistence and chronicity in adults.

Original languageEnglish
Article number100724
JournalWorld Allergy Organization Journal
Volume16
Issue number3
DOIs
Publication statusPublished - Mar 2023

Keywords

  • Atopic dermatitis
  • Epidemiology
  • PO-SCORAD
  • POEM
  • Prevalence
  • Severity

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