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Dietary Polyphenols: Extraction, Identification, Bioavailability, and Role for Prevention and Treatment of Colorectal and Prostate Cancers

  • Naveed Ahmad
  • , Muhammad Qamar
  • , Ye Yuan
  • , Yasir Nazir
  • , Polrat Wilairatana
  • , Mohammad S. Mubarak
  • Multan Medical and Dental College
  • Bahauddin Zakariya University
  • University of Queensland
  • University of Sialkot
  • The University of Jordan

Research output: Contribution to journalReview articlepeer-review

41 Citations (Scopus)

Abstract

Fruits, vegetables, and other edible plants in our diet have numerous health benefits, due to the bioactive compounds in these food items, including polyphenols. These plants are a rich and promising source of natural products and phytochemicals that can be used to treat and prevent numerous diseases and prevent the progression of cancer. Dietary polyphenols exhibit chemo-preventive and therapeutic effects against various ailments, including several types of cancer. The current study focuses on polyphenol’s traditional and advanced extraction methods, with supercritical extraction as a novel approach. It also deals with their identification, bioavailability, and role in preventing and treating colorectal and prostate cancers. Additionally, the article covers the literature that deals with the anticancer activities of polyphenols, as well as their potential use as anticancer agents.

Original languageEnglish
Article number2831
JournalMolecules
Volume27
Issue number9
DOIs
Publication statusPublished - 1 May 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • apoptosis
  • bioavailability
  • cell viability
  • colorectal cancer
  • extraction technique
  • minimum half-inhibitory concentration
  • polyphenols
  • prostate cancer

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