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Chemical constituents of Croton pierrei Gagnep.

  • Chavi Yenjai
  • , Suthasinee Pitchayawasin
  • , Somnuk Bunsupa
  • , Sureeya Sangkul
  • Khon Kaen University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

Extract of the root of Croton pierrei Gagnep. was studied for their cytotoxic activity. Dichloromethane and methanol extracts were found to be strongly active against KB, BC and NCI-H187 cell lines with ED50 of 0.05-4.03 μg/ml. Fractionation of dichloromethane extract led us to isolate friedelin (1), stigmasterol (2), heptadecanoin (3) and isoscopoletin (4). The chemical structures of these compounds were elucidated using spectroscopic methods, mainly 1D and 2D NMR. This is the first report of the chemical constituents from this plant.

Original languageEnglish
Title of host publicationIII WOCMAP Congress on Medicinal and Aromatic Plants - Volume 3
Subtitle of host publicationPerspectives in Natural Product Chemistry
PublisherInternational Society for Horticultural Science
Pages123-125
Number of pages3
ISBN (Print)9789066055186
DOIs
Publication statusPublished - 2005
Externally publishedYes

Publication series

NameActa Horticulturae
Volume677
ISSN (Print)0567-7572

Keywords

  • Friedelin
  • Heptadecanoin
  • Isoscopoletin
  • Stigmasterol

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