Cardiac contractility assessment in rotary blood pump recipients derived from pump flow

P. Naiyanetr; F. Moscato; M. Vollkron; P. Zrunek; G. Wieselthaler; H. Schima

doi:10.1007/978-3-642-03885-3_121

Cardiac contractility assessment in rotary blood pump recipients derived from pump flow

P. Naiyanetr
, F. Moscato
, M. Vollkron
, P. Zrunek
, G. Wieselthaler
, H. Schima

Medical University of Vienna
Ludwig Boltzmann Cluster for Cardiovascular Research

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A new cardiac contractility index derived from pump flow (IQ) has been developed for rotary blood pumps (RBPs) recipients, to determine preservation and eventual recovery of the remaining cardiac function. Pulse flow indices were used for comparison with IQ during pump speed changes. Pump flow was recorded in animal experiments and clinically in RBP recipients (MicroMed DeBakey LVAD®) at different pump speeds. I_Q was derived from the maximal derivative of pump flow versus QP2P relationship (dQ/dt_max vs. QP2P) during speed variations. I_Q was compared to classical indices. Further, simple currently used parameters such as peak to peak of pump flow (QP2P) and pulsation index (PI = QP2P divided by mean pump flow) were calculated. I_Q was speed-independent for both pumps, and correlated well in animal experiments with classical invasively measured contractility index. Simple parameters (QP2P and PI) depended on speed and could be used only for estimation of percentage of support, but not for characterization of cardiac contractility. In conclusion the cardiac contractility index I_Q can be derived from pump flow (I_Q) only. It allows easy and noninvasive continuous access to cardiac function.

Original language	English
Title of host publication	World Congress on Medical Physics and Biomedical Engineering
Subtitle of host publication	Diagnostic and Therapeutic Instrumentation, Clinical Engineering
Publisher	Springer Verlag
Pages	434-437
Number of pages	4
Edition	7
ISBN (Print)	9783642038846
DOIs	https://doi.org/10.1007/978-3-642-03885-3_121
Publication status	Published - 2009
Externally published	Yes
Event	World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering - Munich, Germany Duration: 7 Sept 2009 → 12 Sept 2009

Publication series

Name	IFMBE Proceedings
Number	7
Volume	25
ISSN (Print)	1680-0737

Conference

Conference	World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering
Country/Territory	Germany
City	Munich
Period	7/09/09 → 12/09/09

Keywords

Cardiac contractility index
Cardiac recovery
Pulsitility index and LVAD
Rotary blood pump

Access to Document

10.1007/978-3-642-03885-3_121

Cite this

Naiyanetr, P., Moscato, F., Vollkron, M., Zrunek, P., Wieselthaler, G., & Schima, H. (2009). Cardiac contractility assessment in rotary blood pump recipients derived from pump flow. In World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering (7 ed., pp. 434-437). (IFMBE Proceedings; Vol. 25, No. 7). Springer Verlag. https://doi.org/10.1007/978-3-642-03885-3_121

@inproceedings{96129065462749f3b55612c77b9c9ffb,

title = "Cardiac contractility assessment in rotary blood pump recipients derived from pump flow",

abstract = "A new cardiac contractility index derived from pump flow (IQ) has been developed for rotary blood pumps (RBPs) recipients, to determine preservation and eventual recovery of the remaining cardiac function. Pulse flow indices were used for comparison with IQ during pump speed changes. Pump flow was recorded in animal experiments and clinically in RBP recipients (MicroMed DeBakey LVAD{\textregistered}) at different pump speeds. IQ was derived from the maximal derivative of pump flow versus QP2P relationship (dQ/dtmax vs. QP2P) during speed variations. IQ was compared to classical indices. Further, simple currently used parameters such as peak to peak of pump flow (QP2P) and pulsation index (PI = QP2P divided by mean pump flow) were calculated. IQ was speed-independent for both pumps, and correlated well in animal experiments with classical invasively measured contractility index. Simple parameters (QP2P and PI) depended on speed and could be used only for estimation of percentage of support, but not for characterization of cardiac contractility. In conclusion the cardiac contractility index IQ can be derived from pump flow (IQ) only. It allows easy and noninvasive continuous access to cardiac function.",

keywords = "Cardiac contractility index, Cardiac recovery, Pulsitility index and LVAD, Rotary blood pump",

author = "P. Naiyanetr and F. Moscato and M. Vollkron and P. Zrunek and G. Wieselthaler and H. Schima",

year = "2009",

doi = "10.1007/978-3-642-03885-3\_121",

language = "English",

isbn = "9783642038846",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

number = "7",

pages = "434--437",

booktitle = "World Congress on Medical Physics and Biomedical Engineering",

edition = "7",

note = "World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering ; Conference date: 07-09-2009 Through 12-09-2009",

}

Naiyanetr, P, Moscato, F, Vollkron, M, Zrunek, P, Wieselthaler, G & Schima, H 2009, Cardiac contractility assessment in rotary blood pump recipients derived from pump flow. in World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering. 7 edn, IFMBE Proceedings, no. 7, vol. 25, Springer Verlag, pp. 434-437, World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering, Munich, Germany, 7/09/09. https://doi.org/10.1007/978-3-642-03885-3_121

Cardiac contractility assessment in rotary blood pump recipients derived from pump flow. / Naiyanetr, P.; Moscato, F.; Vollkron, M. et al.
World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering. 7. ed. Springer Verlag, 2009. p. 434-437 (IFMBE Proceedings; Vol. 25, No. 7).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Cardiac contractility assessment in rotary blood pump recipients derived from pump flow

AU - Naiyanetr, P.

AU - Moscato, F.

AU - Vollkron, M.

AU - Zrunek, P.

AU - Wieselthaler, G.

AU - Schima, H.

PY - 2009

Y1 - 2009

N2 - A new cardiac contractility index derived from pump flow (IQ) has been developed for rotary blood pumps (RBPs) recipients, to determine preservation and eventual recovery of the remaining cardiac function. Pulse flow indices were used for comparison with IQ during pump speed changes. Pump flow was recorded in animal experiments and clinically in RBP recipients (MicroMed DeBakey LVAD®) at different pump speeds. IQ was derived from the maximal derivative of pump flow versus QP2P relationship (dQ/dtmax vs. QP2P) during speed variations. IQ was compared to classical indices. Further, simple currently used parameters such as peak to peak of pump flow (QP2P) and pulsation index (PI = QP2P divided by mean pump flow) were calculated. IQ was speed-independent for both pumps, and correlated well in animal experiments with classical invasively measured contractility index. Simple parameters (QP2P and PI) depended on speed and could be used only for estimation of percentage of support, but not for characterization of cardiac contractility. In conclusion the cardiac contractility index IQ can be derived from pump flow (IQ) only. It allows easy and noninvasive continuous access to cardiac function.

AB - A new cardiac contractility index derived from pump flow (IQ) has been developed for rotary blood pumps (RBPs) recipients, to determine preservation and eventual recovery of the remaining cardiac function. Pulse flow indices were used for comparison with IQ during pump speed changes. Pump flow was recorded in animal experiments and clinically in RBP recipients (MicroMed DeBakey LVAD®) at different pump speeds. IQ was derived from the maximal derivative of pump flow versus QP2P relationship (dQ/dtmax vs. QP2P) during speed variations. IQ was compared to classical indices. Further, simple currently used parameters such as peak to peak of pump flow (QP2P) and pulsation index (PI = QP2P divided by mean pump flow) were calculated. IQ was speed-independent for both pumps, and correlated well in animal experiments with classical invasively measured contractility index. Simple parameters (QP2P and PI) depended on speed and could be used only for estimation of percentage of support, but not for characterization of cardiac contractility. In conclusion the cardiac contractility index IQ can be derived from pump flow (IQ) only. It allows easy and noninvasive continuous access to cardiac function.

KW - Cardiac contractility index

KW - Cardiac recovery

KW - Pulsitility index and LVAD

KW - Rotary blood pump

UR - https://www.scopus.com/pages/publications/77949847822

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DO - 10.1007/978-3-642-03885-3_121

M3 - Conference contribution

AN - SCOPUS:77949847822

SN - 9783642038846

T3 - IFMBE Proceedings

SP - 434

EP - 437

BT - World Congress on Medical Physics and Biomedical Engineering

PB - Springer Verlag

T2 - World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering

Y2 - 7 September 2009 through 12 September 2009

ER -

Naiyanetr P, Moscato F, Vollkron M, Zrunek P, Wieselthaler G, Schima H. Cardiac contractility assessment in rotary blood pump recipients derived from pump flow. In World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering. 7 ed. Springer Verlag. 2009. p. 434-437. (IFMBE Proceedings; 7). doi: 10.1007/978-3-642-03885-3_121

Cardiac contractility assessment in rotary blood pump recipients derived from pump flow

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Keywords

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