Benzopyran, biphenyl, and tetraoxygenated xanthone derivatives from the twigs of Garcinia nigrolineata

Vatcharin Rukachaisirikul; Kwanruthai Tadpetch; Anyarat Watthanaphanit; Neangnoi Saengsanae; Souwalak Phongpaichit

doi:10.1021/np058050a

Benzopyran, biphenyl, and tetraoxygenated xanthone derivatives from the twigs of Garcinia nigrolineata

Vatcharin Rukachaisirikul
, Kwanruthai Tadpetch
, Anyarat Watthanaphanit
, Neangnoi Saengsanae
, Souwalak Phongpaichit

Prince of Songkla University
Nakon Si Tammarat Rajabhat University

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

One new benzopyran, nigrolineabenzopyran A (1), two new biphenyls, nigrolineabiphenyls A and B (2, 3), and four new tetraoxygenated xanthones, nigrolineaxanthones T-W (4-7), were isolated from the crude methanol extract of the twigs of Garcinia nigrolineata along with 11 known xanthones. The xanthones isolated from the twigs as well as those from the stem bark were evaluated for antibacterial activity against methicillin-resistant Staphylococcus aureus. Nigrolineaxanthone F, latisxanthone D, and brasilixanthone showed significant activity, with an equal MIC value of 2 μg/mL.

Original language	English
Pages (from-to)	1218-1221
Number of pages	4
Journal	Journal of Natural Products
Volume	68
Issue number	8
DOIs	https://doi.org/10.1021/np058050a
Publication status	Published - Aug 2005
Externally published	Yes

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title = "Benzopyran, biphenyl, and tetraoxygenated xanthone derivatives from the twigs of Garcinia nigrolineata",

abstract = "One new benzopyran, nigrolineabenzopyran A (1), two new biphenyls, nigrolineabiphenyls A and B (2, 3), and four new tetraoxygenated xanthones, nigrolineaxanthones T-W (4-7), were isolated from the crude methanol extract of the twigs of Garcinia nigrolineata along with 11 known xanthones. The xanthones isolated from the twigs as well as those from the stem bark were evaluated for antibacterial activity against methicillin-resistant Staphylococcus aureus. Nigrolineaxanthone F, latisxanthone D, and brasilixanthone showed significant activity, with an equal MIC value of 2 μg/mL.",

author = "Vatcharin Rukachaisirikul and Kwanruthai Tadpetch and Anyarat Watthanaphanit and Neangnoi Saengsanae and Souwalak Phongpaichit",

year = "2005",

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doi = "10.1021/np058050a",

language = "English",

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T1 - Benzopyran, biphenyl, and tetraoxygenated xanthone derivatives from the twigs of Garcinia nigrolineata

AU - Rukachaisirikul, Vatcharin

AU - Tadpetch, Kwanruthai

AU - Watthanaphanit, Anyarat

AU - Saengsanae, Neangnoi

AU - Phongpaichit, Souwalak

PY - 2005/8

Y1 - 2005/8

N2 - One new benzopyran, nigrolineabenzopyran A (1), two new biphenyls, nigrolineabiphenyls A and B (2, 3), and four new tetraoxygenated xanthones, nigrolineaxanthones T-W (4-7), were isolated from the crude methanol extract of the twigs of Garcinia nigrolineata along with 11 known xanthones. The xanthones isolated from the twigs as well as those from the stem bark were evaluated for antibacterial activity against methicillin-resistant Staphylococcus aureus. Nigrolineaxanthone F, latisxanthone D, and brasilixanthone showed significant activity, with an equal MIC value of 2 μg/mL.

AB - One new benzopyran, nigrolineabenzopyran A (1), two new biphenyls, nigrolineabiphenyls A and B (2, 3), and four new tetraoxygenated xanthones, nigrolineaxanthones T-W (4-7), were isolated from the crude methanol extract of the twigs of Garcinia nigrolineata along with 11 known xanthones. The xanthones isolated from the twigs as well as those from the stem bark were evaluated for antibacterial activity against methicillin-resistant Staphylococcus aureus. Nigrolineaxanthone F, latisxanthone D, and brasilixanthone showed significant activity, with an equal MIC value of 2 μg/mL.

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SN - 0163-3864

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SP - 1218

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JO - Journal of Natural Products

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IS - 8

ER -

Benzopyran, biphenyl, and tetraoxygenated xanthone derivatives from the twigs of Garcinia nigrolineata

Abstract

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