Abstract
Autoimmune haemolytic anaemia (AIHA) is characterized by premature destruction of erythrocytes by autoantibodies acting against one's own red blood cell (RBC) antigens. The hallmark of this disorder is a positive direct Coombs test (also referred to as direct antiglobulin test, DAT) from which the causative immune complexes can be sub-identified into immunoglobulin (Ig) G, IgM and complement C3d. The disease manifestations and treatment options vary, depending on the aetiology of AIHA and DAT profile.
| Original language | English |
|---|---|
| Title of host publication | A Guide to Paediatric Red Blood Cell Disorder |
| Publisher | Nova Science Publishers, Inc. |
| Pages | 105-114 |
| Number of pages | 10 |
| ISBN (Electronic) | 9781536187458 |
| ISBN (Print) | 9781536186956 |
| Publication status | Published - 29 Oct 2020 |
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