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Autoimmune haemolytic anaemia

  • University of Kelaniya

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Autoimmune haemolytic anaemia (AIHA) is characterized by premature destruction of erythrocytes by autoantibodies acting against one's own red blood cell (RBC) antigens. The hallmark of this disorder is a positive direct Coombs test (also referred to as direct antiglobulin test, DAT) from which the causative immune complexes can be sub-identified into immunoglobulin (Ig) G, IgM and complement C3d. The disease manifestations and treatment options vary, depending on the aetiology of AIHA and DAT profile.

Original languageEnglish
Title of host publicationA Guide to Paediatric Red Blood Cell Disorder
PublisherNova Science Publishers, Inc.
Pages105-114
Number of pages10
ISBN (Electronic)9781536187458
ISBN (Print)9781536186956
Publication statusPublished - 29 Oct 2020

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