Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats

Panas Tumkiratiwong; Rungsunn Tungtrongchitr; Panata Migasena; Praneet Pongpaew; Wichit Rojekittikhun; Niyomsri Vudhivai; Anchalee Tungtrongchitr; Benjaluck Phonrat; Supaporn Nuamtanong

Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats

Panas Tumkiratiwong
, Rungsunn Tungtrongchitr
, Panata Migasena
, Praneet Pongpaew
, Wichit Rojekittikhun
, Niyomsri Vudhivai
, Anchalee Tungtrongchitr
, Benjaluck Phonrat
, Supaporn Nuamtanong

Department of Parasitology

Siriraj Hospital
Faculty of Tropical Medicine, Mahidol University

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The erythrocyte antioxidant enzyme levels of catalase, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of riboflavin-deficient and Trichinella spiralis-infected rats were investigated. The rats were deprived of riboflavin at the 8^th week of the experiment. At that time, the erythrocyte glutathione reductase activity coefficient (EGR AC), as an indicator of riboflavin status, was ≥ 1.30 in rats fed a riboflavin- deficient diet and T. spiralis-infected rats fed a riboflavin-deficient diet showed no biochemical sign of riboflavin deficiency. At the 12^th week of the experiment, the levels of catalase, SOD and GSH-Px were significantly lower in the riboflavin-deficient, T. spiralis-infected, and combined riboflavin-deficient and T. spiralis-infected, rats, compared to the control group. This may have been due to an increase in free oxygen radicals caused by riboflavin deficiency and parasitic infection.

Original language	English
Pages (from-to)	480-485
Number of pages	6
Journal	Southeast Asian Journal of Tropical Medicine and Public Health
Volume	34
Issue number	3
Publication status	Published - Sept 2003

Cite this

@article{677783fafff54e8fad8afe4d9e7d3c78,

title = "Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats",

abstract = "The erythrocyte antioxidant enzyme levels of catalase, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of riboflavin-deficient and Trichinella spiralis-infected rats were investigated. The rats were deprived of riboflavin at the 8th week of the experiment. At that time, the erythrocyte glutathione reductase activity coefficient (EGR AC), as an indicator of riboflavin status, was ≥ 1.30 in rats fed a riboflavin- deficient diet and T. spiralis-infected rats fed a riboflavin-deficient diet showed no biochemical sign of riboflavin deficiency. At the 12th week of the experiment, the levels of catalase, SOD and GSH-Px were significantly lower in the riboflavin-deficient, T. spiralis-infected, and combined riboflavin-deficient and T. spiralis-infected, rats, compared to the control group. This may have been due to an increase in free oxygen radicals caused by riboflavin deficiency and parasitic infection.",

author = "Panas Tumkiratiwong and Rungsunn Tungtrongchitr and Panata Migasena and Praneet Pongpaew and Wichit Rojekittikhun and Niyomsri Vudhivai and Anchalee Tungtrongchitr and Benjaluck Phonrat and Supaporn Nuamtanong",

year = "2003",

month = sep,

language = "English",

volume = "34",

pages = "480--485",

journal = "Southeast Asian Journal of Tropical Medicine and Public Health",

issn = "0125-1562",

publisher = "SEAMEO TROPMED Network",

number = "3",

}

TY - JOUR

T1 - Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats

AU - Tumkiratiwong, Panas

AU - Tungtrongchitr, Rungsunn

AU - Migasena, Panata

AU - Pongpaew, Praneet

AU - Rojekittikhun, Wichit

AU - Vudhivai, Niyomsri

AU - Tungtrongchitr, Anchalee

AU - Phonrat, Benjaluck

AU - Nuamtanong, Supaporn

PY - 2003/9

Y1 - 2003/9

N2 - The erythrocyte antioxidant enzyme levels of catalase, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of riboflavin-deficient and Trichinella spiralis-infected rats were investigated. The rats were deprived of riboflavin at the 8th week of the experiment. At that time, the erythrocyte glutathione reductase activity coefficient (EGR AC), as an indicator of riboflavin status, was ≥ 1.30 in rats fed a riboflavin- deficient diet and T. spiralis-infected rats fed a riboflavin-deficient diet showed no biochemical sign of riboflavin deficiency. At the 12th week of the experiment, the levels of catalase, SOD and GSH-Px were significantly lower in the riboflavin-deficient, T. spiralis-infected, and combined riboflavin-deficient and T. spiralis-infected, rats, compared to the control group. This may have been due to an increase in free oxygen radicals caused by riboflavin deficiency and parasitic infection.

AB - The erythrocyte antioxidant enzyme levels of catalase, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of riboflavin-deficient and Trichinella spiralis-infected rats were investigated. The rats were deprived of riboflavin at the 8th week of the experiment. At that time, the erythrocyte glutathione reductase activity coefficient (EGR AC), as an indicator of riboflavin status, was ≥ 1.30 in rats fed a riboflavin- deficient diet and T. spiralis-infected rats fed a riboflavin-deficient diet showed no biochemical sign of riboflavin deficiency. At the 12th week of the experiment, the levels of catalase, SOD and GSH-Px were significantly lower in the riboflavin-deficient, T. spiralis-infected, and combined riboflavin-deficient and T. spiralis-infected, rats, compared to the control group. This may have been due to an increase in free oxygen radicals caused by riboflavin deficiency and parasitic infection.

UR - https://www.scopus.com/pages/publications/0347600797

M3 - Article

C2 - 15115116

AN - SCOPUS:0347600797

SN - 0125-1562

VL - 34

SP - 480

EP - 485

JO - Southeast Asian Journal of Tropical Medicine and Public Health

JF - Southeast Asian Journal of Tropical Medicine and Public Health

IS - 3

ER -

Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats

Abstract

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