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Angiotensin-Converting Enzyme Inhibitor-Induced Non-allergic Perioral Angioedema: A Case-Based Scoping Review

  • University Hospital of Giessen and Marburg
  • Chulalongkorn University
  • Hôpital Henri Mondor

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Patients with angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema (ACEIIA) may visit family physicians. The aim of this article was to describe a case of delayed-onset ACEIIA and to present a concise scoping review. Using a case report and a scoping review study design, we report a case of ACEIIA, with clinically confirmed diagnosis. The symptoms resolved after replacing the offending ACEI with another antihypertensive agent. After excluding other causes of perioral swelling and discontinuation of ACEI, the patient was symptom-free within a few days thereafter. Based on this case presentation, we performed a meta-narrative scoping review including up-todate diagnosis and management of ACEIIA, based on published data in English, French, and German from inception to April 1, 2021. Patients with angioedema of unknown origin should be cautiously examined to rule out oral diseases, including allergy to dental materials and drug-induced angioedema.

Original languageEnglish
Pages (from-to)2-10
Number of pages9
JournalKorean Journal of Family Medicine
Volume44
Issue number1
DOIs
Publication statusPublished - 2023

Keywords

  • Angioedema
  • Angiotensin-Converting Enzyme Inhibitors
  • Oral Medicine
  • Review

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