An enantioselective organocatalytic route to chiral 3,6-dihydropyridazines from aldehydes

Alexander J. Oelke; Sirirat Kumarn; Deborah A. Longbottom; Steven V. Ley

doi:10.1055/s-2006-951486

An enantioselective organocatalytic route to chiral 3,6-dihydropyridazines from aldehydes

Alexander J. Oelke
, Sirirat Kumarn
, Deborah A. Longbottom
, Steven V. Ley

University of Cambridge

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

Here we describe a highly enantioselective organocatalytic synthesis of chiral 3,6-dihydropyridazines from achiral starting materials which proceeds with good yield via a one-pot procedure.

Original language	English
Pages (from-to)	2548-2552
Number of pages	5
Journal	Synlett
Issue number	16
DOIs	https://doi.org/10.1055/s-2006-951486
Publication status	Published - 4 Oct 2006
Externally published	Yes

Keywords

Asymmetric catalysis
Heterocycles
Ring closure
Tandem reactions
Wittig reaction

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10.1055/s-2006-951486

Cite this

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title = "An enantioselective organocatalytic route to chiral 3,6-dihydropyridazines from aldehydes",

abstract = "Here we describe a highly enantioselective organocatalytic synthesis of chiral 3,6-dihydropyridazines from achiral starting materials which proceeds with good yield via a one-pot procedure.",

keywords = "Asymmetric catalysis, Heterocycles, Ring closure, Tandem reactions, Wittig reaction",

author = "Oelke, \{Alexander J.\} and Sirirat Kumarn and Longbottom, \{Deborah A.\} and Ley, \{Steven V.\}",

year = "2006",

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doi = "10.1055/s-2006-951486",

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T1 - An enantioselective organocatalytic route to chiral 3,6-dihydropyridazines from aldehydes

AU - Oelke, Alexander J.

AU - Kumarn, Sirirat

AU - Longbottom, Deborah A.

AU - Ley, Steven V.

PY - 2006/10/4

Y1 - 2006/10/4

N2 - Here we describe a highly enantioselective organocatalytic synthesis of chiral 3,6-dihydropyridazines from achiral starting materials which proceeds with good yield via a one-pot procedure.

AB - Here we describe a highly enantioselective organocatalytic synthesis of chiral 3,6-dihydropyridazines from achiral starting materials which proceeds with good yield via a one-pot procedure.

KW - Asymmetric catalysis

KW - Heterocycles

KW - Ring closure

KW - Tandem reactions

KW - Wittig reaction

UR - https://www.scopus.com/pages/publications/33750040576

U2 - 10.1055/s-2006-951486

DO - 10.1055/s-2006-951486

M3 - Article

AN - SCOPUS:33750040576

SN - 0936-5214

SP - 2548

EP - 2552

JO - Synlett

JF - Synlett

IS - 16

ER -

An enantioselective organocatalytic route to chiral 3,6-dihydropyridazines from aldehydes

Abstract

Keywords

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