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A three-year clinical study on immunogenicity, safety, and booster response of purified chick embryo cell rabies vaccine administered intramuscularly or intradermally to 12- to 18-month-old thai children, concomitantly with japanese encephalitis vaccine

  • Krisana Pengsaa
  • , Kriengsak Limkittikul
  • , Arunee Sabchareon
  • , Churdchoo Ariyasriwatana
  • , Pornthep Chanthavanich
  • , Phanosri Attanath
  • , Claudius Malerczyk
  • Faculty of Tropical Medicine, Mahidol University
  • Queen Sirikit National Institute of Child Health
  • Novartis Vaccines and Diagnostics GmbH & Co.KG

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

After concomitant administration of purified chick embryo cell rabies vaccine and Japanese encephalitis vaccine to toddlers, adequate rabies and Japanese encephalitis virus neutralizing antibodies concentrations were demonstrated by day 49, 7 days after a booster at 1 year, and in the majorly at 3 years postvaccination. The inclusion of rabies vaccine in the expanded program on immunization should be considered in rabies endemic countries.

Original languageEnglish
Pages (from-to)335-337
Number of pages3
JournalPediatric Infectious Disease Journal
Volume28
Issue number4
DOIs
Publication statusPublished - Apr 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Anamnestic response
  • JE virus-neutralizing antibody
  • Pre-exposure prophylaxis
  • Rabies vaccination
  • Rabies virus neutralizing antibody

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