A novel NAD+/MWNTs nanocomposite-based electrochemical biosensor for measuring mevalonic acid

Rungtiva Palangsuntikul; Saithip Pakapongpan; Porntip Khownarumit; Werasak Surareungchai

doi:10.4028/www.scientific.net/KEM.605.388

A novel NAD⁺/MWNTs nanocomposite-based electrochemical biosensor for measuring mevalonic acid

Rungtiva Palangsuntikul
, Saithip Pakapongpan
, Porntip Khownarumit
, Werasak Surareungchai

K. Mongkut's Univ. Technol. Thonburi
National Electronics and Computer Technology Center

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Citations (Scopus)

Abstract

A novel, simple and precise electrochemical biosensor, was developed for measuring mevalonic acid (MA) concentration, which is thought to be a good indicator of HMG-CoA reductase activity. This sensor is based on noncovalent-linking NAD+/MWNTs nanocomposite coated on a screen-printed electrode (SPE). The resulting biosensor exhibited excellent electrocatalytic activity, fast response and good stability to MA. At the NAD+/MWNTs-modified SPE, the current is linear with the concentration of MA being within a concentration range from 18.1 to 145 μM with a limit of detection down to 4.25 μM (S/N = 3), and the sensor exhibited a sensitivity of 92.2 μA/mM.

Original language	English
Title of host publication	Materials and Applications for Sensors and Transducers III
Publisher	Trans Tech Publications Ltd
Pages	388-391
Number of pages	4
ISBN (Print)	9783038350514
DOIs	https://doi.org/10.4028/www.scientific.net/KEM.605.388
Publication status	Published - 2014
Externally published	Yes
Event	3rd International Conference on Materials and Applications for Sensors and Transducers, IC-MAST 2013 - Prague, Czech Republic Duration: 13 Sept 2013 → 17 Sept 2013

Publication series

Name	Key Engineering Materials
Volume	605
ISSN (Print)	1013-9826
ISSN (Electronic)	1662-9795

Conference

Conference	3rd International Conference on Materials and Applications for Sensors and Transducers, IC-MAST 2013
Country/Territory	Czech Republic
City	Prague
Period	13/09/13 → 17/09/13

Keywords

Electrochemical sensor
MWNTs
Mevalonic acid
Nanocomposite

Access to Document

10.4028/www.scientific.net/KEM.605.388

Cite this

Palangsuntikul, R., Pakapongpan, S., Khownarumit, P., & Surareungchai, W. (2014). A novel NAD⁺/MWNTs nanocomposite-based electrochemical biosensor for measuring mevalonic acid. In Materials and Applications for Sensors and Transducers III (pp. 388-391). (Key Engineering Materials; Vol. 605). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.605.388

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title = "A novel NAD+/MWNTs nanocomposite-based electrochemical biosensor for measuring mevalonic acid",

abstract = "A novel, simple and precise electrochemical biosensor, was developed for measuring mevalonic acid (MA) concentration, which is thought to be a good indicator of HMG-CoA reductase activity. This sensor is based on noncovalent-linking NAD+/MWNTs nanocomposite coated on a screen-printed electrode (SPE). The resulting biosensor exhibited excellent electrocatalytic activity, fast response and good stability to MA. At the NAD+/MWNTs-modified SPE, the current is linear with the concentration of MA being within a concentration range from 18.1 to 145 μM with a limit of detection down to 4.25 μM (S/N = 3), and the sensor exhibited a sensitivity of 92.2 μA/mM.",

keywords = "Electrochemical sensor, MWNTs, Mevalonic acid, Nanocomposite",

author = "Rungtiva Palangsuntikul and Saithip Pakapongpan and Porntip Khownarumit and Werasak Surareungchai",

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language = "English",

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series = "Key Engineering Materials",

publisher = "Trans Tech Publications Ltd",

pages = "388--391",

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Palangsuntikul, R, Pakapongpan, S, Khownarumit, P & Surareungchai, W 2014, A novel NAD⁺/MWNTs nanocomposite-based electrochemical biosensor for measuring mevalonic acid. in Materials and Applications for Sensors and Transducers III. Key Engineering Materials, vol. 605, Trans Tech Publications Ltd, pp. 388-391, 3rd International Conference on Materials and Applications for Sensors and Transducers, IC-MAST 2013, Prague, Czech Republic, 13/09/13. https://doi.org/10.4028/www.scientific.net/KEM.605.388

A novel NAD⁺/MWNTs nanocomposite-based electrochemical biosensor for measuring mevalonic acid. / Palangsuntikul, Rungtiva; Pakapongpan, Saithip; Khownarumit, Porntip et al.
Materials and Applications for Sensors and Transducers III. Trans Tech Publications Ltd, 2014. p. 388-391 (Key Engineering Materials; Vol. 605).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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