A new oxoaporphine alkaloid from the root of dasymaschalon glaucum

Weerachai Silprakob; Nuntaporn Sukhamsri; Chutima Kuhakarn; Sakchai Hongthong; Surawat Jariyawat; Kanoknetr Suksen; Radeekorn Akkarawongsapat; Jitra Limthongkul; Narong Nantasaen; Vichai Reutrakul

doi:10.1177/1934578x1801301115

A new oxoaporphine alkaloid from the root of dasymaschalon glaucum

Weerachai Silprakob
, Nuntaporn Sukhamsri
, Chutima Kuhakarn
, Sakchai Hongthong
, Surawat Jariyawat
, Kanoknetr Suksen
, Radeekorn Akkarawongsapat
, Jitra Limthongkul
, Narong Nantasaen
, Vichai Reutrakul

University of Phayao
Mahidol University
Wildlife and Plant Conservation Department

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The first phytochemical investigation of the root of Dasymaschalon glaucum led to the isolation of a new oxoaporphine alkaloid 1 together with seven known compounds, duguevalline (2), stigmalactam (3), enterocarpam III (4), desmosdumotin B (5), spiraeamide (6), kaempferol-3-O-glucopyranoside (7) and β-sitosterol (8). The chemical structures of all isolated compounds were established on the basis of their spectroscopic data. The cytotoxic and anti-HIV 1-RT activities of isolated compounds were also evaluated.

Original language	English
Pages (from-to)	1471-1474
Number of pages	4
Journal	Natural Product Communications
Volume	13
Issue number	11
DOIs	https://doi.org/10.1177/1934578x1801301115
Publication status	Published - Nov 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Annonaceae
Anti-HIV
Aristolactam
Cytotoxic
Dasymaschalon glaucum
Oxoaporphine

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10.1177/1934578x1801301115

Cite this

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title = "A new oxoaporphine alkaloid from the root of dasymaschalon glaucum",

abstract = "The first phytochemical investigation of the root of Dasymaschalon glaucum led to the isolation of a new oxoaporphine alkaloid 1 together with seven known compounds, duguevalline (2), stigmalactam (3), enterocarpam III (4), desmosdumotin B (5), spiraeamide (6), kaempferol-3-O-glucopyranoside (7) and β-sitosterol (8). The chemical structures of all isolated compounds were established on the basis of their spectroscopic data. The cytotoxic and anti-HIV 1-RT activities of isolated compounds were also evaluated.",

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doi = "10.1177/1934578x1801301115",

language = "English",

volume = "13",

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T1 - A new oxoaporphine alkaloid from the root of dasymaschalon glaucum

AU - Silprakob, Weerachai

AU - Sukhamsri, Nuntaporn

AU - Kuhakarn, Chutima

AU - Hongthong, Sakchai

AU - Jariyawat, Surawat

AU - Suksen, Kanoknetr

AU - Akkarawongsapat, Radeekorn

AU - Limthongkul, Jitra

AU - Nantasaen, Narong

AU - Reutrakul, Vichai

PY - 2018/11

Y1 - 2018/11

N2 - The first phytochemical investigation of the root of Dasymaschalon glaucum led to the isolation of a new oxoaporphine alkaloid 1 together with seven known compounds, duguevalline (2), stigmalactam (3), enterocarpam III (4), desmosdumotin B (5), spiraeamide (6), kaempferol-3-O-glucopyranoside (7) and β-sitosterol (8). The chemical structures of all isolated compounds were established on the basis of their spectroscopic data. The cytotoxic and anti-HIV 1-RT activities of isolated compounds were also evaluated.

AB - The first phytochemical investigation of the root of Dasymaschalon glaucum led to the isolation of a new oxoaporphine alkaloid 1 together with seven known compounds, duguevalline (2), stigmalactam (3), enterocarpam III (4), desmosdumotin B (5), spiraeamide (6), kaempferol-3-O-glucopyranoside (7) and β-sitosterol (8). The chemical structures of all isolated compounds were established on the basis of their spectroscopic data. The cytotoxic and anti-HIV 1-RT activities of isolated compounds were also evaluated.

KW - Annonaceae

KW - Anti-HIV

KW - Aristolactam

KW - Cytotoxic

KW - Dasymaschalon glaucum

KW - Oxoaporphine

UR - https://www.scopus.com/pages/publications/85057819871

U2 - 10.1177/1934578x1801301115

DO - 10.1177/1934578x1801301115

M3 - Article

AN - SCOPUS:85057819871

SN - 1934-578X

VL - 13

SP - 1471

EP - 1474

JO - Natural Product Communications

JF - Natural Product Communications

IS - 11

ER -

A new oxoaporphine alkaloid from the root of dasymaschalon glaucum

Abstract

UN SDGs

Keywords

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