A new bibenzyl-phenanthrene derivative from Dendrobium signatum and its cytotoxic activity

Arparporn Mittraphab; Chawanphat Muangnoi; Kittisak Likhitwitayawuid; Pornchai Rojsitthisak; Boonchoo Sritularak

doi:10.1177/1934578x1601100526

A new bibenzyl-phenanthrene derivative from Dendrobium signatum and its cytotoxic activity

Arparporn Mittraphab
, Chawanphat Muangnoi
, Kittisak Likhitwitayawuid
, Pornchai Rojsitthisak
, Boonchoo Sritularak

Chulalongkorn University

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

From the whole plant of Dendrobium signatum, a new bibenzyl-dihydrophenanthrene derivative, named dendrosignatol was isolated, together with the known compounds 3,4-dihydroxy-3,4'-dimethoxybibenzyl, dendrocandin B, dendrocandin I and dendrofalconerol A. The structure of the new compound was elucidated through analysis of its spectroscopic and mass spectrometric data. All of the isolates showed appreciable cytotoxic activity against three human cancer cell lines, including MDA-231, HepG2 and HT-29 cells.

Original language	English
Pages (from-to)	657-659
Number of pages	3
Journal	Natural Product Communications
Volume	11
Issue number	5
DOIs	https://doi.org/10.1177/1934578x1601100526
Publication status	Published - May 2016
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Bibenzyl-dihydrophenanthrene
Cytotoxicity
Dendrobium signatum
Orchidaceae

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10.1177/1934578x1601100526

Cite this

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title = "A new bibenzyl-phenanthrene derivative from Dendrobium signatum and its cytotoxic activity",

abstract = "From the whole plant of Dendrobium signatum, a new bibenzyl-dihydrophenanthrene derivative, named dendrosignatol was isolated, together with the known compounds 3,4-dihydroxy-3,4'-dimethoxybibenzyl, dendrocandin B, dendrocandin I and dendrofalconerol A. The structure of the new compound was elucidated through analysis of its spectroscopic and mass spectrometric data. All of the isolates showed appreciable cytotoxic activity against three human cancer cell lines, including MDA-231, HepG2 and HT-29 cells.",

keywords = "Bibenzyl-dihydrophenanthrene, Cytotoxicity, Dendrobium signatum, Orchidaceae",

author = "Arparporn Mittraphab and Chawanphat Muangnoi and Kittisak Likhitwitayawuid and Pornchai Rojsitthisak and Boonchoo Sritularak",

year = "2016",

month = may,

doi = "10.1177/1934578x1601100526",

language = "English",

volume = "11",

pages = "657--659",

journal = "Natural Product Communications",

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T1 - A new bibenzyl-phenanthrene derivative from Dendrobium signatum and its cytotoxic activity

AU - Mittraphab, Arparporn

AU - Muangnoi, Chawanphat

AU - Likhitwitayawuid, Kittisak

AU - Rojsitthisak, Pornchai

AU - Sritularak, Boonchoo

PY - 2016/5

Y1 - 2016/5

N2 - From the whole plant of Dendrobium signatum, a new bibenzyl-dihydrophenanthrene derivative, named dendrosignatol was isolated, together with the known compounds 3,4-dihydroxy-3,4'-dimethoxybibenzyl, dendrocandin B, dendrocandin I and dendrofalconerol A. The structure of the new compound was elucidated through analysis of its spectroscopic and mass spectrometric data. All of the isolates showed appreciable cytotoxic activity against three human cancer cell lines, including MDA-231, HepG2 and HT-29 cells.

AB - From the whole plant of Dendrobium signatum, a new bibenzyl-dihydrophenanthrene derivative, named dendrosignatol was isolated, together with the known compounds 3,4-dihydroxy-3,4'-dimethoxybibenzyl, dendrocandin B, dendrocandin I and dendrofalconerol A. The structure of the new compound was elucidated through analysis of its spectroscopic and mass spectrometric data. All of the isolates showed appreciable cytotoxic activity against three human cancer cell lines, including MDA-231, HepG2 and HT-29 cells.

KW - Bibenzyl-dihydrophenanthrene

KW - Cytotoxicity

KW - Dendrobium signatum

KW - Orchidaceae

UR - https://www.scopus.com/pages/publications/84982134955

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DO - 10.1177/1934578x1601100526

M3 - Article

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AN - SCOPUS:84982134955

SN - 1934-578X

VL - 11

SP - 657

EP - 659

JO - Natural Product Communications

JF - Natural Product Communications

IS - 5

ER -

A new bibenzyl-phenanthrene derivative from Dendrobium signatum and its cytotoxic activity

Abstract

UN SDGs

Keywords

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